The United Nations Theme Group on HIV/AIDS (WHO, UNICEF, UNDP, World Bank, UNIFEM, IOM, UNODC, UNHCR, ILO), working under the leadership of the UN Resident Coordinator, chaired by WHO, with UNICEF as vice chair, and facilitated by the UNAIDS Country Coordinator, constitutes UNAIDS at country level. The UNAIDS Secretariat operates as a catalyst and coordinator of UN actions on AIDS.

The overarching goal of UNAIDS in Nigeria is to support the country to achieve the Millennium Development Goal No. 6 on HIV/AIDS.Specific objectives and key results for 2004-2006 include fostering leadership for an effective response and to track, monitor and evaluate the country response, strengthening partnerships and coordination mechanisms, promoting and strengthening the management of strategic information, mainstreaming HIV/AIDS into development frameworks and mobilizing technical and financial resources.